The cytochrome P450 superfamily (CYP) is a large and diverse group of enzymes. The function of most CYP enzymes is to catalyze the oxidation of organic substances. The substrates of CYP enzymes include metabolic intermediates such as lipids and steroidal hormones, as well as xenobiotic substances such as drugs and other toxic chemicals. CYPs are the major enzymes involved in drug metabolism and bioactivation, accounting for about 75% of the total number of different metabolic reactions.
CYP1 Drug and steroid (especially estrogen) metabolism 3 subfamilies, 3 genes, 1 pseudogene CYP1A1, CYP1A2, CYP1B1
CYP2 Drug and steroid metabolism 13 subfamilies, 16 genes, 16 pseudogene CYP2A6, CYP2A7, CYP2A13, CYP2B6, CYP2C8, CYP2C9, CYP2C18, CYP2C19, CYP2D6, CYP2E1, CYP2F1, CYP2J2, CYP2R1, CYP2S1, CYP2U1, CYP2W1
CYP3 Drug and steroid (including testosterone) metabolism 1 subfamily, 4 genes, 2 pseudogenes CYP3A4, CYP3A5, CYP3A7, CYP3A43
CYP4 Arachidonic acid or fatty acid metabolism 6 subfamilies, 12 genes, 10 pseudogenes CYP4A11, CYP4A22, CYP4B1, CYP4F2, CYP4F3, CYP4F8, CYP4F11, CYP4F12, CYP4F22, CYP4V2, CYP4X1, CYP4Z1
CYP5 Thromboxane A2 synthase 1 subfamily, 1 gene CYP5A1
CYP7 Bile acid biosynthesis 7-alpha hydroxylase of steroid nucleus 2 subfamilies, 2 genes CYP7A1, CYP7B1
CYP8 Varied 2 subfamilies, 2 genes CYP8A1 (prostacyclin synthase), CYP8B1 (bile acid biosynthesis)
CYP11 Steroid biosynthesis 2 subfamilies, 3 genes CYP11A1, CYP11B1, CYP11B2
CYP17 Steroid biosynthesis, 17-alpha hydroxylase 1 subfamily, 1 gene CYP17A1
CYP19 Steroid biosynthesis: aromatase synthesizes estrogen 1 subfamily, 1 gene CYP19A1
CYP20 Unknown function 1 subfamily, 1 gene CYP20A1
CYP21 Steroid biosynthesis 2 subfamilies, 1 gene, 1 pseudogene CYP21A2
CYP24 Vitamin D degradation 1 subfamily, 1 gene CYP24A1
CYP26 Retinoic acid hydroxylase 3 subfamilies, 3 genes CYP26A1, CYP26B1, CYP26C1
CYP27 Varied 3 subfamilies, 3 genes CYP27A1 (bile acid biosynthesis), CYP27B1 (vitamin D3 1-alpha hydroxylase, activates vitamin D3), CYP27C1 (unknown function)
CYP39 7-alpha hydroxylation of 24-hydroxycholesterol 1 subfamily, 1 gene CYP39A1
CYP46 Cholesterol 24-hydroxylase 1 subfamily, 1 gene CYP46A1
CYP46 Cholesterol biosynthesis 1 subfamily, 1 gene, 3 pseudogenes CYP51A1 (lanosterol 14-alpha demethylase)

Synonyms: Sophoretin,Meletin,Quercetine,Xanthaurine,Quercetol,Quercitin,Quertine,Flavin meletin

Read more: Quercetin, dihydrate

Synonyms: Omeprazole, INN, Antra, Losec, Audazol, Omapren, Belmazol, Ceprandal, Emeproton, Gastrimut, Indurgan

Read more: Omeprazole

Synonyms: Diltiazem, Cardizem, Dilacorxr, Tiazac, Cardizem

Read more: Diltiazem hydrochloride

Synonyms: Clotrimazole, Lotriminaf, Mycelex, Canesten, Lotrimin, CLT

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Synonyms: 8-Phenyltheophylline, 8-Phenyl-1,3-dimethylxanthine, 8-PT

Read more: 8-Phenyltheophylline hydrochloride

Synonyms: Terfenadine, Seldane, Triludan, Teldane

Read more: Terfenadine

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